Variolla

A. DEFINITIONS

Variola is an infectious disease in humans caused by the variola virus variola major or minor. The disease is known by its Latin name, or variola variola vera, which originates from the Latin varius, meaning "speckled", or varus, meaning "pimple".
Variola appeared on the small blood vessels in the skin and in the mouth and esophagus. In the skin, it causes a rash, and then wound with fluid. Variola major cause more serious disease with a mortality rate of 30-35%. Variola minor causes a milder disease (also known as alastrim, cottonpox, milkpox, whitepox, and Cuban itch) which causes death in 1% of sufferers. Long-term consequences of infection is variola major scars, usually on the face, which occurs in 65-85% sufferer.

B. ANATOMY PHYSIOLOGY

1) The epidermis (Kutilkula) is the outermost layer of skin, which has a thin structure with a thickness of 0.07 mm made up of several layers, among others, as follows: Stratum corneum layer of a substance which is also called horns.
a) The location is in the outer layer and is the dead skin. Epidermal tissue was prepared by 50 layers of dead cells, and will experience pengelupasansecara slowly, replaced with a new egg.
b) Stratum lusidum, which function is to "paint" the skin and hair. The more melanin produced by these cells, the skin color will become increasingly dark.
c) Stratum granulosum, which produce skin pigment, called melamine. This layer consists of living cells and is located at the bottom of the epidermal tissue.
d) Stratum germinativum, often described as living cells because this layer is the active layer splitting. The cells divide outwards to form the skin cells teluar. The cells will encourage the newly formed cells which were above the next cell will also be driven from below by newer cells again. At the same time the cells of the outermost layer of peeling and fall.

2) Network dermis has a more complicated structure than the epidermis, which consists of many layers. This network is thicker than the epidermis, which is about 2.5 mm. Dermis formed by special fibers that make it flexible, which consists of collagen, a type of protein that make up about 30% of body protein. Collagen will gradually decrease with age. That is why an old man who had a rough skin texture and wrinkles. Dermis layer lies below the epidermis layer. Dermis layer consists of the following sections. Hair follicle and surrounding structure.
a) Root hairs.
b) Blood vessels.
c) the oil glands (sebaceous glands) there are around hair roots. The existence of these oil glands to keep the hair is not dry.
d) sweat glands (glands sudorifera)
e) Nerves

C. Etiology

Poxviruses known viruses virus type 2 is almost identical but cause 2 types of variola, variola major and variola minor.

D. CLINICAL SYMPTOMS

1. Heat 6.Berwarna redness.
2. Dizziness 7.Bentol have reddish bumps.
3. No appetite
4. Diotot and bone pain
5. Skin rash